9 results
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
reactions. ... lgE causes mast-cell ... reaction, Haemolytic ... recruitment of leucocytes ... #reactions #types
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Reactions: • Immune ... Reaction (FNHTR ... Reaction (AHTR) ... Reaction (DHTR) ... #diagnosis #management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Reactions Immune ... Reaction (FNHTR ... Reaction (AHTR) ... • Allergic reaction ... #diagnosis #management
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... released during an allergic ... reaction or asthma ... basophilic leukemia Hypersensitivity ... Or Inflammatory Reactions
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Reactions TRALI ... of high parity blood ... without other cause ... #Reactions #hematology ... #diagnosis #comparison
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... destruction after transfusion ... Classification #Pathophysiology ... #Allergy #Diagnosis ... #Reactions #Table
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
transfusion • ... Allergic reaction ... • Intracranial blood ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... transfusion • ... protein C and S Pathophysiology ... #Coagulation #diagnosis ... #management #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
transfusion, Hypercalcemia ... Etiology: • Pathophysiology ... elevated white blood ... the underlying cause ... #management #neurology