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hematology differential cord management neurology spinal spinalcord agglutinin algorithm aplastic cryofibrinogenemia disease disorders hemolytic lesions oncology reactions rhabdomyolysis syndromes taco
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... Clinical Presentation ... anemia • Cold ... Mycoplasma, EBV, HIV ... #hematology #diagnosis
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
decades of life Causes ... and clinical associations ... Infections 2. ... #rheumatology # ... comparison #table
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... Idiopathic • Infections ... • Improve the symptoms ... #diagnosis #management
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... Infarction - Infection ... syphilis, and HIV ... #differential #diagnosis ... #neurology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... without other cause ... symptoms • Fever ... #diagnosis #comparison ... #table
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... Causes: 1. ... Infections: - ... HIV, CMV, HTLV ... MCTD, Sjogren syndrome
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... Malignancy • Infections ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #rheumatology #
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Statins - ETOH - Infection ... - Viral (HIV, Influenza ... Dermatomyositis Clinical ... #treatment #nephrology
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