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hematology management differential blood cord neurology product spinal spinalcord transfusion algorithm anemia cryofibrinogenemia disorders immune inflammatory iris lesions oncology reconstitution
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Anemia Clinical ... and petechiae Causes ... Idiopathic • Infections ... • Improve the symptoms ... #diagnosis #management
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
decades of life Causes ... and clinical associations ... Infections 2. ... #rheumatology # ... comparison #table
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... without other cause ... symptoms • Fever ... #hematology #diagnosis ... #comparison #table
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Product Types: • Leukocyte ... proteins on plts, leukocytes ... TRALI resembles ARDS ... due to marrow aplasia ... #Transfusions #diagnosis
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
proteins on plts, leukocytes ... TRALI resembles ARDS ... due to marrow aplasia ... Infection - Infection ... #Transfusion #diagnosis
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
- Differential Diagnosis ... neurological lesion: Clinical ... Causes: 1. ... Infections: - ... MCTD, Sjogren syndrome
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... Infarction - Infection ... syphilis, and HIV ... #differential #diagnosis ... #neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... /AIDS patients ... be present: • AIDS ... initiation Clinical ... : • Drug reaction
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... Malignancy • Infections ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #rheumatology #
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Statins - ETOH - Infection ... - Viral (HIV, Influenza ... Dermatomyositis Clinical ... #treatment #nephrology
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