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hematology anemia hemolytic oncology atlas bloodcell classification cold disease extravascular hodgkins intravascular macrocytosis management markers mds microscopy myelodysplasia myelodysplastic nomenclature
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Diagnosis Algorithm ... Normal Blood Smear ... Myelodysplastic Syndromes ... Diagnosis #Algorithm ... #Causes #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Diagnosis Algorithm ... - Abnormal morphology ... #Disorders #hematology ... #Diagnosis #Algorithm
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology ... Microcytic RBC: ... Unstable hemoglobin disorders ... #Morphology #differential ... #diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Syndrome (CAS): ... or lymphoid malignancy ... Diagnosis: • hemolytic ... younger pts) Differential ... #anemia #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
e.g. lupus, CLL, lymphoma ... . primary cold agglutin ... • Intrinsic RBC ... #differential # ... diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... other reproducible morphologic ... membrane disorder ... #Diagnosis #Algorithm ... #workup #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... for workup, including ... #Diagnosis #Algorithm ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... nodosum • Immune hemolytic ... Workup: • Full ... Treatment • Early ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
caused by blood ... formed or don’t work ... common cytopenia: Macrocytic ... differential • ... #diagnosis #hematology
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