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sle signs vasculitis ana antibodies antinuclear behcet chronic classification cll dermatology lymphocytic macrophage mas mds monoclonal myelodysplasia myelodysplastic pancytopenia paraproteinemias
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Wiskott-Aldrich syndrome ... Cancer: • Leukemia ... : • Systemic lupus ... erythematosus ... #Diagnosis #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... lupus erythematosus ... : • Symptoms limited ... #Lupus #Erythematosus ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Associated with skin ... #Lupus #Erythematosus ... #rheumatology # ... management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... lupus erythematosus ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Demyelinating syndromes ... #erythematosus # ... signs #symptoms ... #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... ANA #patterns #rheumatology ... #diagnosis #differential
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Hematology #Oncology ... #Diagnosis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... symptoms by days ... - Lupus - Leukemia ... #diagnosis #dermatology ... #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Diagnosis: Systemic ... lupus erythematosus ... Symptoms (Sx) in ... , and SLE) • Urinalysis ... #diagnosis #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... with no early symptoms ... Hepatomegaly • Skin ... cells can indicate disease ... #oncology #hematology
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