20 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... lupus erythematosus ... Xeroderma (Dry skin ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Small Vessel Vasculitides
 • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
Interstitial lung disease ... lupus erythematosus ... , and Sjogren's ... in absence of skin ... #diagnosis
Seronegative Inflammatory Arthritis - Differential Diagnosis
 • Seronegative Rheumatoid Arthritis 
 • Infectious Arthritis: Viral, Bacterial,
: Systemic Lupus ... Erythematous, Systemic ... Vasculitis, Systemic ... Sclerosis, Sjogren's ... #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(15%) Skin (85% ... Butterfly rash, Vasculitis ... #erythematosus # ... signs #symptoms ... #diagnosis #rheumatology
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
- systemic ... lupus erythematosus ... - Sjögren ... #Rheumatology # ... Diagnosis
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Associated with skin ... heart block • Sjogren ... #Lupus #Erythematosus ... management
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... lupus erythematosus ... (SLE), Sjogren's ... lupus erythematosus ... : Lupus (SLE), Systemic
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... dermatomyositis, Sjogren ... lupus erythematosus ... #Lupus #Erythematosus ... #Diagnosis #Rheumatology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
Visual or auditory symptoms ... conjunction with symptoms ... central nervous system ... lupus erythematosus ... ANCA-associated vasculitides
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: erythematous nodules ... as systemic lupus ... erythematosus, ... Symptoms (Sx) in ... , and SLE) • Urinalysis