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diagnosis causes pruritus systemic dermatology generalized secondary thrombocytosis anemia approach cbc ckd classification cll disorders erythematosus hemodialysis lupus lymphocytic management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Chronic leukemia ... extramedullary disease ... - infiltrates (anemia ... #Hematology #Oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Thrombocytosis - Differential ... Diagnosis Algorithm ... Myelogenous Leukemia ... disorders • Celiac disease ... Iron deficiency anemia
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Blood Loss ... • Anemia of Chronic ... Disease • Marrow ... #Causes #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Diagnosis Algorithm ... / Systemic == Blood ... Creatinine & BUN: • Chronic ... • Lymphoma • Leukemia ... Diagnosis #Algorithm
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... : Acute blood loss ... Vasculitides, IBD, Celiac disease ... • Infections: Chronic
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... - Markers and Differential ... Diagnosis Algorithm ... T-cell - CD7, CD3 Chronic ... #Disorders #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... cells can indicate disease ... Lymphocytosis: Absolute blood ... diagnosis #workup #oncology ... #hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... leukocytes. ... Tissue damage • Leukemia ... • Autoimmune diseases ... neutrophil #WBC #CBC #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Diagnosis Algorithm ... Blood Glucose ... Creatinine & BUN: • Chronic ... • Lymphoma • Leukemia ... #generalized #dermatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... Myeloproliferative Disease ... count with differential ... Syndromes #diagnosis #hematology ... #oncology
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