21 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... hematuria. ... RBC casts in urine ... but in severe cases ... #Nephrology #Diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
and/or proteinuria ... (RBC casts or dysmorphic ... RBCs in urine)? ... #Comparison #Algorithm ... #Nephrology #Diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Fanconi's syndrome ... sediment - WBC/RBC casts ... Minimal change disease ... #Algorithm #Causes
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Diagnosis Framework ... basement membrane disease ... : - RBC casts ... - Proteinuria ... of glomerular disease
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... glomerular bleeding (proteinuria ... , RBC casts, dysmorphic ... Nephrology if cause ... #Diagnosis #Algorithm
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
Algorithm and Differential ... Hematuria Important ... RBC’s, RBC/WBC casts ... , proteinuria suggest ... intrinsic renal disease
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... blood cells on urine ... RBCs and/or RBC casts ... nephrotic range) proteinuria ... #Algorithm #Causes
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... hemolytic-uremic syndrome ... cell/white cell casts ... cluster, the diseases ... Hematuria may be
Urinalysis & Urine Sodium 
Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
proteins, documenting proteinuria ... as a disease state ... • Urinary casts ... #urine #UNa #casts ... #glucosuria #hematuria
Causes Abnormal Urine Color - Differential Diagnosis
Turbid White Urine (Albinuria):
 • Chyluria, Filariasis, Schistosomiasis, Malignancy, Phosphaturia,
Causes Abnormal ... Diagnosis Turbid ... Hyperoxalirua, Heavy Proteinuria ... • Hartnup disease ... : • Hematuria,