39 results
Lower Urinary Tract Infection: Pathogenesis and Clinical Findings

- Predisposing Factors:  Immunocompromised state, diabetes, elderly, female
Lower Urinary Tract ... epithelium -> Lower ... (+) Nitrites, Leukocyte ... Hematuria (rare) #Lower ... UrinaryTractInfection #LUTI #Pathophysiology
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... also be seen if urine ... glomerular disease • Leukocytes ... to 3 per high-power ... contamination #Urine
Urinalysis & Urine Sodium 
Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
Urinalysis & Urine ... • Ketones • Leukocyte ... • Urinary casts ... dipstick #nitrite #leucocyte-esterase ... #urine #UNa #casts
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Hematuria: Red/Dark urine ... 1ml blood/liter urine ... hematuria + clots ➔ Lower ... examination of urine ... Bladder (Upper and Lower
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
Purple Urine Bag ... E.coli*) + alkaline urine ... BrighamChiefs #Purple #Urine ... Syndrome #PUBS #pathophysiology ... #clinical #photo
Lower Urinary Tract Infections: Complications
 - Infection damages the urinary tract epithelium causing fibroblast proliferation and
Lower Urinary Tract ... Infection of the lower ... urea which may cause ... supersaturation of urine ... UrinaryTractInfection #LUTI #Pathophysiology
Distal Renal Tubular Acidosis (RTA)  Type 1 

Totally scuppers the kidney's acidification mechanism. Will be
diagnosis with direct urine ... Failure to acidify urine ... secretion Cannot lower ... Management #Nephrology #Causes
Causes of Dysuria - Differential Diagnosis Algorithm
Pyuria - Leukocytes on Dipstick/Microscopy
 - Bacteriuria & Hematuria -
Causes of Dysuria ... Algorithm Pyuria - Leukocytes ... • Lower ... No Pyuria - No Leukocytes ... Diagnosis #Algorithm #Causes
Granular & “Muddy Brown” Casts on Urine Microscopy
A. Finely granular cast B. slightly coarser granular cast
on Urine Microscopy ... “urine poker quads ... appreciated at low power ... compared to high power ... #Urine #Microscopy
Urine Microscopy Instructions
1) Spin fresh urine sample (10-15mL) in a centrifuge for 3-5 minutes - Don't
Urine Microscopy ... 1) Spin fresh urine ... whole slide under lower ... power (casts may ... iMedEducation #Urine