29 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome ... lymphocytic lymphoma (SLL ... #Leukemia #Hematology
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... proportion of the red blood ... three peripheral blood ... well as varying clinical ... majority of the leukocytes
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... Abnormalities: macrocytic anemia ... (12%) • giant cell ... including peripheral blood ... Autoinflammatory #Somatic #rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Orange or Hep C Clinical ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... workup #oncology #hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Demyelinating syndromes ... Glomerulonephritis Myositis(5%) Blood ... (75%): Anemia ( ... symptoms #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
) Clinical Manifestations ... Demyelinating Syndrome ... thrombosis and/or blood-brain ... #CNS #neurology ... #rheumatology #
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... sensitize red blood ... passage of red-brown urine ... #hematology #diagnosis
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
neuritis - Giant cell ... - SLE Neurologic ... arteritis • Bloody ... pulses - Giant cell ... differential #diagnosis #rheumatology
Hematuria in Post-Renal Transplant Patient
Prevalence up to 12% in the postrenal transplant patient
 • Bacterial: Escherichia
HPV, EBV), Renal cell ... (Goodpasture's syndrome ... , SLE, IgA nephropathy ... diagnosis #kidney #blood ... #urine #management
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... 5) Symptoms of anemia ... marrow failure with anemia ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management