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diagnosis rheumatology joint pain msk workup adultonset anemia approach autoimmune conditions erythematosus extrarticular hemolytic hodgkins laboratory lupus lymphoma monoarthritis monoarticular
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Jaundice - Hepatitis ... Antiphospholipid-antibody ... • Bloody or ... #joint #pain #differential ... #diagnosis #rheumatology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
↑ LDH • Anti-RBC ... type ± C3d • Blood ... smear: Differential ... Anemia #diagnosis #management ... #treatment #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Fever, Arthralgia/arthritis ... fraction < 20% Differential ... hepatomegaly, hepatitis ... #diagnosis #management ... #treatment #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... , erythema and WBC ... effusion with few WBCs ... morning • Effusion leukocyte ... B19 • HIV • Hepatitis
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
), RA, crystal disease ... • Bloody: Trauma ... tumor • Non-bloody ... parvovirus, HIV, hepatitis ... approach #workup #differential
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Polyarthritis: • Blood ... IgM) levels • Hepatitis ... : • Complete blood ... count (CBC) • ... ) • Hepatitis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... pulses, bruis, or blood ... Large Vessel: Blood ... Lab Tests: • CBC ... #classification
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
w differential ... , Anti-GBM antibody ... reveals increasing blood ... #diagnosis #management ... #treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... Noninfectious hepatitis ... titers > 1:80 • CBC
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
platelets - WBC ... number of sites of disease ... Hodgkin Lymphoma Treatment ... #hematology #oncology ... #management
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