182 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
• Placenta • Leukocytes ... biliary Cholangitis (PBC ... granulamatous disease ... - Infiltrative diseases ... Other biliary diseases
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... peripheral blood leukocytes ... • Autoimmune diseases ... Even with normal WBC ... likelihood of negative clinical
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... • Blasts > 10% leukocytes ... Splenomegaly • ↑ Leukocyte ... AML Dx: • ↑ Leukocyte ... Leukemia #Hematology #Oncology
Lower Urinary Tract Infection: Pathogenesis and Clinical Findings

- Predisposing Factors:  Immunocompromised state, diabetes, elderly, female
Pathogenesis and Clinical ... Malaise, Incr WBC ... CFU/L) Incr WBC ... (>10 WBC/gL) ... (+) Nitrites, Leukocyte
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Diagnosis and Management ... Summary Clinical ... demineralization) • Renal disease ... Myeloma #Diagnosis #Management ... #oncology
Urinalysis & Urine Sodium 
Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
proteinuria as a disease ... • Ketones • Leukocyte ... Red blood cells (RBC ... dipstick #nitrite #leucocyte-esterase
B-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Clinical
 - Primarily a disease of childhood, 75% <6 yo
 - Increased
Lymphoblastic Lymphoma Clinical ... - Primarily a disease ... extramedullary disease ... Traditionally based age, WBC ... Patients with higher WBC
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
RBC are produced ... destruction of RBC ... 150,000 per mcL, and leukocytes ... well as varying clinical ... majority of the leukocytes
Von Willebrand Disease - Clinical Presentation, Diagnosis and Management

- Dr. Eric Strong @DrEricStrong - Strong Medicine
Von Willebrand Disease ... - Clinical Presentation ... Diagnosis and Management ... VonWillebrand #Disease ... #Diagnosis #Management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
if high risk if WBC ... QD until normal WBC ... APML #diagnosis #management ... #hematology #oncology