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differential causes criticalcare injury kidney nephrology overview acidosis coagulation dic disseminated diuresis diuretics elevation encephalopathy excretion foamed fungal hematology infections
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
- Classification ... cardiorenal syndrome) • Liver ... causes: sepsis, meds ... prolonged prerenal AKI ... #diagnosis #nephrology
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
Diagnosis Framework ... Insufficiency, Liver ... Treatment Goals ... #criticalcare #algorithm ... #treatment #management
Acute Kidney Injury (AKI) - Management Principles Prerenal - Correct hemodynamic derangements: • If low preload →
Acute Kidney Injury ... (AKI) - Management ... Treat underlying liver ... Medications → Stop meds ... #management
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
anaphylaxis, toxins/meds ... • Other: AI, ... thyroid dz liver ... #Classification ... #diagnosis #management
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
anaphylaxis, toxins/meds ... • Other: AI, ... thyroid dz liver ... #Classification ... #diagnosis #management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
glucose by the liver ... contribution of liver ... mellitus/DKA - Liver ... gluconeogenesis Liver ... #typea #typeb #classification
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
irrigation • Management ... heart failure, liver ... heart failure, liver ... heart failure, liver ... heart failure, liver
5-Oxoprolinuria What is it: • Aka pyroglutamic acidosis, Intermediate in γ-glutamyl cycle • Amino acid transport and
What is it: • Aka ... • Concomitant acute ... deficiency) • Liver ... HAGMA; Paracetamol level ... #management #treatment
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
which all carry treatment ... stores in the liver ... beta-oxidation in the liver ... #diagnosis #differential ... #algorithm #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Infection/Sepsis/Shock ... syndrome, ADEM, Acute ... elevated protein level ... persistent altered level ... #management #neurology
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