48 results
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
vary depending on treatment ... mortality at a higher level ... Therapeutic #Ranges #Toxicology ... #Pharmacology #
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
no respiratory cause ... , Diaphoresis, Pulmonary ... Toxic Salicylate Level ... Aspirin #Toxicity #Toxicology ... diagnosis #management #Treatment
Pharmacologic treatment algorithms by Global Initiative for Chronic Obstructive Lung Disease grade. Highlighted boxes and arrows
Pharmacologic treatment ... indicate preferred treatment ... the perceived level ... #Management #Pulmonary
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... : 33% • Treatment ... , and CXR with pulmonary ... : No • Treatment ... Transfusion #Reactions #hematology
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... patients who have treatment-resistant ... metabolized in the liver ... Clozapine is known to cause ... Toxicity #Diagnosis #Pharmacology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... by case) • Surgery ... #management #pharmacology ... #rheumatology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Renal Failure • Liver ... Chronic Obstructive Pulmonary ... Myasthenia Gravis Pharmacologic ... Diagnosis #Algorithm #causes
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... hepatitis • Pulmonary ... diagnosis #management #treatment ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
, ↓ Fibrinogen level ... Drugs, Unknown cause ... Treatment: • ... diagnosis #management #treatment ... #summary #rheumatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
glucose by the liver ... / hypoxemia -> focus ... perfusion - shock->treatments ... before beginning treatment ... output - Acute pulmonary