32 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
peripheral blood smear, HIV ... : INR/PT, aPTT(liver ... changes), high MCV anemia ... bypass), LFT (liver ... #Workup #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
for Hemolytic Anemia ... : • Liver disease ... Rhogam • S/p IV ... #Hemolytic #Anemia ... classification #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... immunodeficiency virus (HIV ... index < 2 • EPO Level ... Treatment: ... #oncology #hematology
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
• Prodrome: fever ... • Autopsy PCR Treatment ... diagnosis #management #treatment ... #microbiology # ... infectiousdiseases
Visceral Leishmaniasis - Diagnosis and Management Summary
Species: Leishmania donovani, Leishmania infantum, Leishmania chagasi
Where: South Asia, East
2-6 months • Fever ... Weight Loss • Can cause ... Lymphohistiocytosis • Anemia ... #infectiousdiseases ... #microbiology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... deficiency • Liver ... • HCV, HBV Not ... mountain spotted fever ... #rheumatology #
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Renal Failure • Liver ... Hematologic • Anemia ... Hepatitis • HIV ... Myasthenia Gravis Pharmacologic
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
elevation • Nausea ... 14%), in which case ... • Viral RNA level ... enzymes ↑ • Mild anemia ... antibody test) Treatment
Cyclosporiasis - Diagnosis and Management Summary
Pathogen: 
 • Cyclospora cayetanensis
 • Foodborne, waterbone, and soil-transmitted.
 •
Immunocompromised host (HIV ... • Anorexia, Nausea ... diarrhea, Low-grade fever ... #microbiology # ... infectiousdiseases
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Infections in HIV ... macrophages in HIV ... factor • May cause ... ), anemia, arthralgia ... differential #diagnosis #infectiousdiseases