21 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... splenomegaly • Hepatic ... hepatitis • Pulmonary ... Disease #diagnosis #management ... #treatment #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... DIC • Severe Liver ... Treat primary cause ... #treatment #management ... #hematology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
symptoms • Rheumatologic ... has five major clinical ... stain of clinical ... normal glucose level ... #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
+++ (Plt, Hb), Hepatic ... , ↓ Fibrinogen level ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... renal failure Clinical ... symptoms are not caused ... Pulmonary: dyspnea ... heart (2-5%), liver
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
the setting of liver ... lung disease Caused ... shunt (Type 2) Clinical ... • Underlying liver ... hypertension • Liver
Blastomycosis (Blastomyces): Gilchrist’s disease, Chicago disease - Summary Sheet
 • Morphology
 • Geography, Reservoir and Mode
& Mississippi river ... - Sporadic cases ... inoculation • Clinical ... Diagnosis • Management ... #summary #fungal
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess - Clinical ... decubitus - air fluid level ... Prevotella • Fungal ... Lung #Abscess #pulmonary
Hepatic Hydrothorax
 • Presents as right sided in 85% of cases
 • Fluid studies:
Hepatic Hydrothorax ... sided in 85% of cases ... may develop • Management ... TIPS, Liver transplant ... diagnosis #hepatology #pulmonary
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... disease • Liver ... Low serum IgG level ... DDX - Other causes ... #diagnosis #management