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diagnosis hepatology management gastroenterology acidosis aclf acute adultonset cardiology causes chronic cirrhosis classification criticalcare disease disorders drug druginduced elevation failure
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced Liver ... Injury (DILI) ... or symptoms of liver ... Drug #induced #Liver ... #differential #
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Injury (DILI) - ... Alcohol-related liver ... #DrugInduced #Liver ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... #differential # ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... Failure (ACLF) Clinical ... months without treatment ... disease, liver ... Injury (DILI)
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
Shock - Differential ... Insufficiency, Liver ... Medications, Spinal Cord Injury ... • Obstructive: Pulmonary ... #criticalcare #algorithm
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... triad: Fever, Arthralgia ... fraction < 20% Differential ... hepatitis • Pulmonary ... diagnosis #management #treatment
Hypertensive Disorders of Pregnancy Chronic Hypertension: • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg •
pits <100k), ↑ liver ... doubling of Cr), pulmonary ... hemolysis, elevated liver ... diagnosis so have high clinical ... obstetrics #cardiology #differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
glucose by the liver ... contribution of liver ... output - Acute pulmonary ... mellitus/DKA - Liver ... gluconeogenesis Liver
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Hematologic malignancy ... Presentation: Fever ... (elevations of liver ... Manifestations: • Fever ... • Fever and weight
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