43 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... parvovirus B19 infection ... • Rheumatic fever ... #rashes #differential ... #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
acute rheumatic fever ... Chronic = RA, SLE ... #rheumatology # ... approach #workup ... #differential #
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Hyperthyroidism Fever ... • Rheumatic fever ... , Rheumatic fever ... • New murmur, fever ... #diagnosis #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Associated - SLE ... mountain spotted fever ... #Diagnosis #hematology ... #rheumatology #
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... • Rheumatic fever ... streptococci (rheumatic fever ... arthritis • SLE ... Diagnosis #MSK #rheumatology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
, Fever, No muscle ... myopathy) VA Joint ... Myopathies #myopathy #differential ... #diagnosis #comparison ... #rheumatology
Approach to a Positive (+) Rheumatoid Factor (RF)
(+) RF does not always = RA
Rheumatic disorders:
 •
arthritis • SLE ... disorders: • Chronic infections ... Inflammatory disorders of Liver ... Rheumatoid #Factor #RF #rheumatology ... #laboratory #differential
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... ) General: Fever ... phenomenon (20%) Joints ... Arthritis in small joints ... symptoms #diagnosis #rheumatology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Fever/Chills/Joint ... arthritis - SLE ... Acute rheumatic fever ... Effusions: - Hematologic
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
genotypes): SS, SC, SE ... inclusions - If infection ... bartonella (oroya fever ... Diagnosis #Algorithm #workup ... #hematology #testing