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diagnosis rheumatology treatment causes criticalcare neurology oncology syndrome algorithm anemia blood cns comparison dermatology hemophagocytic hodgkins infectiousdiseases lymphohistiocytosis lymphoma pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... : fever +++, hepatosplenomegaly ... , ↓ Fibrinogen level ... Lymphohistiocytosis #diagnosis #management
Checklist for Evaluation of New-Onset Delirium in the ICU Initial assessment - Vital signs, neuro exam
Checklist for Evaluation ... - CBC with differential ... Additional tox/infectious ... workup as appropriate ... (fever, leukocytosis
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... can mimic common infections ... following: • Fever ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... ALT ↑ bilirubin level ... #Hematology #Rheumatology
Aortitis - Diagnosis and Workup Clinical History: - Fever, weight loss, deterioration of general health - Aortic
Diagnosis and Workup ... Clinical History ... : - Fever, weight ... on the cause Infections ... #Differential #
Cerebral Toxoplasmosis - Most comrnon CNS infection in patients with AIDS who are not receiving appropriate
Most comrnon CNS infection ... prophylaxis Clinical ... Headache • Fever ... • Seizure Management ... pyrimethamine-induced hematologic
Kerion Raised, boggy lesion with heaped up purulent nodules Caused by host's response to a fungal ringworm
fungal ringworm infection ... mentagrophytes) Clinical ... Hair loss • Fever ... Griseofulvin #Kerion #Dermatology ... #Diagnosis #Management
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... inclusions - If infection ... bartonella (oroya fever ... Diagnosis #Algorithm #workup ... #hematology #testing
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
., HIV), EBV infection ... Autoimmune diseases • Clinical ... - Pel-Ebstein fever ... Etiology: - Infections ... #hematology
Endocarditis checklist Initial evaluation • Peripheral blood cultures (three sets at three different sites) • Additional culture
Endocarditis checklist ... for metastatic infection ... • Persistent fever ... Internet Book of Critical ... #Endocarditis #checklist
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