15 results
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
) Clinical Features ... : Fever, Splenomegaly ... : ↑↑ ferritin, Anemia ... 8 criteria: • Fever ... Lymphohistiocytosis #diagnosis #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... is the main clinical ... - Nonremitting fever ... Diagnosis #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... following: • Fever ... lymph node, or liver ... agent are the main ... management #treatment #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Agglutination - Cold ... bartonella (oroya fever ... Algorithm #workup #hematology
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
neurologic symptoms, fever ... stroke Tuberculous Abscess ... ) • Headache, fever ... Meningitis: • Fever ... Tuberculosis #diagnosis #differential
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
Spinal stenosis - Abscess ... : - Loss of pain ... multiradicular pain ... syndromes #lesions #differential ... #diagnosis #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential ... neurological lesion: Clinical ... continence • Pain ... reported at level ... #differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... younger pts) Differential ... Symptoms: High fevers ... chills, flank pain ... #hematology #diagnosis
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess - Clinical ... : • 80% have fever ... Pleuritic chest pain ... Leukocytosis, anemia ... Intervention: - Fevers
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Autoimmune diseases • Clinical ... - Pel-Ebstein fever ... Alcohol-induced pain ... : Pain in involved ... #hematology