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diagnosis hematology oncology management causes algorithm aplastic chronic cll erythematosus hodgkins lactate lupus lymphocytic lymphoma sle systemic acidosis aids apml
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Script Signs and symptoms ... Treatment: • Consider ... if neutropenic fever ... to MDS or acute leukemia ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... Headaches, bone pain, fever ... - infiltrates (anemia ... Lymphadenopathy • HSM • Fevers ... #Hematology #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Most common leukemia ... → fevers, night ... of anemia or thrombocytopenia ... marrow failure with anemia ... #oncology #hematology
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Pericardial Effusion - Differential ... Non-Infectious: • Rheumatologic ... Mediterranean Fever ... Primary: Lymphoma, Leukemia ... • Metabolic: Uremia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... recurrent infections/fevers ... virus (EBV) • Leukemia ... Treatment: ... • Improve the symptoms
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Lymphadenopathy • Fevers ... • Neutropenia, anemia ... microglobulin Treatment ... #diagnosis #workup
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... bartonella (oroya fever ... Diagnosis #Algorithm #workup ... #hematology #testing
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... myocarditis, rheumatic fever ... Lymphomas • Leukemias ... associated with any symptoms ... Dehydrogenase #Elevated #differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... pylori test (GI symptoms ... changes), high MCV anemia ... #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Malar rash 40% - Fever ... - Hemolytic anemia ... autoantibodies #signs #symptoms ... #mimickers #differential ... #rheumatology
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