63 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
hepatic crisis: • Fever ... acute onset RUQ pain ... cholestasis: • Fever ... Hepatobiliary #hepatology ... #hepatitis #differential
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... parvovirus B19 infection ... • Rheumatic fever ... #rashes #differential ... #diagnosis #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... SLE) - Viral infections ... mountain spotted fever ... #Diagnosis #hematology ... #rheumatology #
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
Malignancy - Night pain ... splenomegaly, abnormal neurology ... , back pain Haematology ... cell disease Rheumatology ... #Child #Peds #Pediatrics
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
e.g., HIV), EBV infection ... - Pel-Ebstein fever ... Alcohol-induced pain ... : Pain in involved ... #hematology
Diagnostic criteria for Neutropenic Enterocolitis (NEC)
Major Criteria:
 • Neutropenia (ANC <500 x 10^9 cells/L)
 • Bowel
30mm length) • Fever ... • Abdominal pain ... Diagnosis #criteria #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Renal Disease, Liver ... Inflammation, Chronic Infection ... Classification #Differential ... Algorithm #Causes #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... Diagnosis #Management #Hematology ... #Rheumatology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Presentation: • Fever ... cæxist with other infections ... Diagnostic Criteria - Fever ... KD #vasculitis #rheumatology ... #pediatrics #diagnossi
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
: • Recurrent infections ... if neutropenic fever ... management #treatment #hematology