7 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Subacute-Acute: • Common: fever ... - pulmonary opacities ... initiation • Differential ... management #hematology #oncology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Cough, Dyspnea, Fever ... symptomatology Differential ... , anti-CCP • CXR ... Renal #Syndrome #differential ... #diagnosis #nephrology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Differentials? ... ABG And BMP Normal ... Anxiety, pain, fever ... Classically” noted with pulmonary ... Diagnosis #Summary #Nephrology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... : Blast crises ... Headaches, bone pain, fever ... manifestations, hypoxia, CXR ... Leukemia #Hematology #Oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Neutropenic fever ... : - Fever + ANC ... Treat underlying cause ... or HSCT - CRS: fever ... therapy - Symptoms: fever
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... : • 80% have fever ... decubitus - air fluid level ... Lung #Abscess #pulmonary ... #differential #
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Management Summary Causes ... Muscle swelling - Fever ... ) • AKI: BUN/Cr ... #treatment #nephrology