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diagnosis management rheumatology dermatology differential lupus oncology disease erythematosus hemophagocytic hlh lymphohistiocytosis syndrome systemic druginduced hemeonc petechiae petechial stills summary
Sweet’s Syndrome - Acute febrile neutrophilic dermatosis The syndrome involves fever, painful rash, neutrophilic leukocytosis, and
Syndrome - Acute febrile ... syndrome involves fever ... , painful rash, ... neutrophilic #dermatosis #dermatology ... #Rash #Skin #Clinical
Vesiculobullous Rashes - THE ALGORITHMIC APPROACH Vesiculobullous rashes provoke significant angst in many physicians (Figure 5, page
Vesiculobullous Rashes - THE ALGORITHMIC ... these rashes as febrile ... and a fever may ... localized lesions and fever ... #Diagnosis #Dermatology
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
or absence of fever ... If fever is present ... disease, scarlet fever ... but without a fever ... #Febrile #Fever
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Fever of Unknown ... Refer to your ‘Fever ... Returning Traveler’ algorithm ... node biopsy • Clinical ... udaygulati #FUO #Fever
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Red Flags: • Fever ... medication Febrile ... deficiency Work ... #Causes #dermatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
correlates with time of fever ... Daily high spiking fever ... - Fever spikes ... Fever of at least ... extremities during febrile
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... erythematosus [SLE ... ALT ↑ bilirubin level
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... • Immunologic Workup ... life-threatening • Treatment ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... • Immunologic Workup ... 40, F:M 9:1 • Clinical ... • Immunologic Workup
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Systemic Lupus (SLE ... ) General: Fever ... Photosensitivity, Butterfly rash ... Thrombocytopenia #Lupus #SLE
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