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Algorithm for Diagnosis of the Vesiculobullous Rash

Febrile, Diffuse Distribution:
 - Varicella,  Smallpox,  Disseminated, Gonococcal,
Algorithm for Diagnosis ... Vesiculobullous Rash ... Hand Foot & Mouth Disease ... #Algorithm #Diagnosis ... #Dermatology #Skin
Vesiculobullous Rashes - THE ALGORITHMIC APPROACH 
Vesiculobullous rashes provoke significant angst
in many physicians (Figure 5, page
Vesiculobullous Rashes - THE ALGORITHMIC ... these rashes as febrile ... and a fever may ... localized lesions and fever ... #Diagnosis #Dermatology
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
or absence of fever ... includes Kawasaki disease ... , scarlet fever, ... #Diagnosis #Dermatology ... #Febrile #Fever
Central Distribution, Febrile / Ill:
 - Viral Exanthem 
 - Lyme Disease (erythema migrans) 
Central Distribution,
Exanthem - Lyme Disease ... Syphilis - Lyme Disease ... Macules #Papules #Rash ... #Algorithm #Diagnosis ... #Dermatology #Skin
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... leishmaniasis • Adult Still's ... : • Still's disease ... by an afebrile ... #Differential #Diagnosis
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... triad: Fever, Arthralgia ... arthritis, Skin rash ... Differential Diaqnoses ... #Disease #diagnosis
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
correlates with time of fever ... Daily high spiking fever ... - Fever spikes ... Fever of at least ... #diagnosis #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Disease (AOSD) ... : High spiking fever ... maculopapular rash ... Systemic AOSD: high fever ... #rheumatology #diagnosis
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis
 • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Causes of Fever ... Brucellosis, Q fever ... Malignancy: - Hematologic ... Sarcoidosis, Adult onset Still's ... , Factitious fever
Adult Onset Still's Disease - Yamaguchi Criteria
Major criteria:
 - Fever >= 39C lasting >= 1 weeks
Adult Onset Still's ... criteria: - Fever ... - Typical skin rash ... with concomitant fever ... #Criteria #Diagnosis