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diagnosis management infectiousdiseases hematology differential cardiology disease syndrome comparison dermatology hemeonc hemophagocytic hlh leukemia lymphohistiocytosis american chagas chronic cll endocarditis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... : fever +++, hepatosplenomegaly ... , ↓ Fibrinogen level ... Treatment: • ... #summary #rheumatology
Hantavirus Pathogen: Hantavirus - Rodents are the primary reservoir Transmission: • Shed in the urine, feces, saliva of
common route of infection ... • Prodrome: fever ... • Autopsy PCR Treatment ... diagnosis #management #treatment ... #microbiology #
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Causes of Pericardial ... , Candida Non-Infectious ... : • Rheumatologic ... Mediterranean Fever ... #cardiology
Interstitial pneumonias An acute reticular pattern is most frequently caused by interstitial edema due to cardiac heart
most frequently caused ... The other cause ... cough and some fever ... This was a PCP-infection ... #Clinical #Radiology
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
Presentation: • Fever ... cæxist with other infections ... Diagnostic Criteria - Fever ... KD #vasculitis #rheumatology ... diagnossi #management #treatment
Kerion Raised, boggy lesion with heaped up purulent nodules Caused by host's response to a fungal ringworm
purulent nodules Caused ... fungal ringworm infection ... mentagrophytes) Clinical ... Hair loss • Fever ... Lymphadenopathy Treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... SLE], AOSD) • Infection ... ALT ↑ bilirubin level
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
confusion and fever ... This is relapsing fever ... Fever recurs over ... Infectious Diseases ... microscopy #pathology #clinical
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... Presentation: • Fever ... and petechiae Causes ... index < 2 • EPO Level ... Aplastic #Anemia #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Neutropenic fever ... : - Fever + ANC ... Treat underlying cause ... or HSCT - CRS: fever ... therapy - Symptoms: fever
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