33 results
Cannon A Waves in AVNRT on Neck Physical Exam

69 year old female patient comes with a
Waves in AVNRT on Neck ... shortness of breath ,fever ... , what’s the clinical ... #PhysicalExam # ... JVP #Cardiology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... syndromes Clinical ... multiorgan failure • Fever ... - Nonremitting fever ... ALT ↑ bilirubin level
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... sequestration and activation ... explain symptoms • Fever ... fluid balance, and CXR ... pulmonary edema) • Fever
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... Inflammation: high fever ... TREATMENT: ​• Acute ... gabrieltalledop #Oroya #Fever ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... - 80% have fever ... organ damage • Treatment ... acid, Elevated Cr ... TLS #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... excessive macrophage activation ... following: • Fever ... Lymphohistiocytosis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... accumulation of clinical ... : fever +++, hepatosplenomegaly ... , ↓ Fibrinogen level ... Lymphohistiocytosis #diagnosis #management
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
Adjuvant therapies in critical ... Pneumonia - Typhoid fever ... respiratory distress syndrome ... #Pharmacology #Management ... #Treatment #Indications
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess - Clinical ... : • 80% have fever ... Blood cultures • CXR ... early disease) • CXR ... decubitus - air fluid level
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... common • Imaging: CXR ... APML #diagnosis #management