35 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... syndromes Clinical ... multiorgan failure • Fever ... - Nonremitting fever ... #Hematology #Rheumatology
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome ... • Clinically ... Diagnosis and Treatment ... #HES #Hematology ... eosinophils #diagnosis #management
Kerion
Raised, boggy lesion with heaped up purulent nodules 
Caused by host's response to a fungal ringworm
mentagrophytes) Clinical ... Hair loss • Fever ... Lymphadenopathy Treatment ... Griseofulvin #Kerion #Dermatology ... #Diagnosis #Management
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
megaloblastic anemia Treatment ... if neutropenic fever ... Anemia #diagnosis #management ... #treatment #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... Low calcium • Treatment ... TLS #diagnosis #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... following: • Fever ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... Presentation: • Fever ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
Adjuvant therapies in critical ... Pneumonia - Typhoid fever ... respiratory distress syndrome ... #Pharmacology #Management ... #Treatment #Indications
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... explain symptoms • Fever ... : 33% • Treatment ... pulmonary edema) • Fever ... Transfusion #Reactions #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... triad: Fever, Arthralgia ... Disease #diagnosis #management ... #treatment #rheumatology