19 results
Janeway Lesions in Endocarditis seen on Physical Exam 

Dr Supradip Ghosh
@dr_supradip

36 year old male with history
left hemiplegia, fevers ... with persistent fever ... #Endocarditis #PhysicalExam ... #clinical #photo ... #dermatology #soles
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... syndromes Clinical ... multiorgan failure • Fever ... - Nonremitting fever ... Treatment: • Corticosteroids
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... triad: Fever, Arthralgia ... • Pulmonary: pleural ... diagnosis #management #treatment ... #rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... Presentation: • Fever ... recurrent infections/fevers ... aplastic anemia Treatment ... Anemia #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... following: • Fever ... • Bicytopenia Treatment ... #hematology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Neutropenic fever ... : - Fever + ANC ... ): - Hematologic ... or HSCT - CRS: fever ... therapy - Symptoms: fever
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Treatment depends ... Actively maintained fever ... • Serotonin syndrome ... amphetamines) Toxic: • Radiologic
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
with or without treatment ... , but without treatment ... ) ▪ Malaise, fever ... Rash #Diagnosis #Clinical ... #Photo #Dermatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... weight loss, and fever ... Clinical Features ... vein thrombosis Hematologic ... to: Arthritis, Fever
Staphylococcal Scalded Skin Syndrome (SSSS) 
(aka Ritter disease) 
Nikolsky positive 
Clinical 
• Typically occurs 3 to
Staphylococcal Scalded Skin Syndrome ... Nikolsky positive Clinical ... Rare at birth • Fever ... mechanical stress (flexural ... CA-MRSA or initial treatment