10 results
Validation of the Step-By-Step Approach to Febrile Infants

#Diagnosis #Management #Pediatrics #Peds #Febrile #Infant #StepByStep #Algorithm #LP
#Management #Pediatrics ... #Peds #Febrile ... #Algorithm #LP ... #Antibiotics #Risk ... Stratification #Fever
Validation of the “Step-by-Step” Approach in the Management of Young Febrile Infants
Visual Abstract by Dr. Kirsty
Approach in the Management ... Infants Visual ... #EBM #Peds #Pediatrics ... #Infant #Risk # ... Stratification #Fever
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... fever without source ... #Pediatrics #Peds ... #Febrile #Infant ... Stratification #Fever
The Febrile Infant Step-by-Step Algorithm
This is an algorithm developed by European emergency physicians to identify low-risk
The Febrile Infant ... empiric antibiotic treatment ... #Pediatrics #Peds ... #Febrile #Infant ... Stratification #Fever
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
frequently affects infants ... acute or subacute febrile ... following: • Fever ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Attempt if high risk ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... APML #diagnosis #management ... #hematology #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... - 80% have fever ... : - If febrile ... TLS #diagnosis #management ... #hematology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Neutropenic fever ... : - Fever + ANC ... mg/dL or > 25 % rise ... or HSCT - CRS: fever ... therapy - Symptoms: fever
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Risk ... • Dyspnea • Fever ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
consideration in febrile ... Characteristics: Persistent fever ... Onset: Usually in infancy ... Persistent high fever ... Fever b.