29 results
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Lymphohistiocytosis (HLH ... Clinical Features: Fever ... : ↑↑ ferritin, Anemia ... 8 criteria: • Fever ... Lymphohistiocytosis #diagnosis #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Treatment: • Consider ... if neutropenic fever ... #diagnosis #management ... #treatment #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... with leukopenia, anemia ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... lymph node, or liver ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Presentation: • Fever ... Diagnostic Criteria - Fever ... KD #vasculitis #rheumatology ... #pediatrics #diagnossi ... #management #treatment
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... recurrent infections/fevers ... Treatment: ... #oncology #hematology ... #diagnosis #management
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
explain symptoms • Fever ... : 33% • Treatment ... fluid balance, and CXR ... pulmonary edema) • Fever ... Transfusion #Reactions #hematology
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... Inflammation: high fever ... severe hemolytic anemia ... TREATMENT: ​• Acute ... gabrieltalledop #Oroya #Fever
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
: High spiking fever ... Systemic AOSD: high fever ... Disease #AOSD #rheumatology ... #diagnosis #management ... #treatment