19 results
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... explain symptoms • Fever ... pulmonary edema) • Fever ... #hematology #diagnosis ... #comparison #table
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... diagnosis #management #hematology ... #oncology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
mountain spotted fever ... • Drug reactions ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... : Blast crises ... Headaches, bone pain, fever ... #Leukemia #Hematology ... #Oncology #Diagnosis
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... have drop in Hct, fever ... Causes purpura & ... Sx include: fever ... diagnosis #management #hematology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Neutropenic fever ... : - Fever + ANC ... Treat underlying cause ... or HSCT - CRS: fever ... therapy - Symptoms: fever
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Drug Reaction with ... Edema in 70% of cases ... Fever >38.5 2. ... disease: symptomatic treatment ... DRESS #Syndrome #dermatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
S/sx: Fever, flank ... have drop in Hct, fever ... Causes purpura & ... Sx include: fever ... diagnosis #management #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... - Pel-Ebstein fever ... #NonHodgkins #comparison ... #oncology #diagnosis ... #differential #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... Actively maintained fever ... CAUSES OF HYPERTHERMIA ... transfusion • Allergic reaction ... amphetamines) Toxic: • Radiologic