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diagnosis management differential hematology cardiology causes syndrome activetb adultonset aosd classification endocarditis infectiousdiseases latenttb summary tb tuberculosis accaha activation adult
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... triad: Fever, Arthralgia ... #AdultOnset #Stills ... #management #treatment ... #rheumatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... : High spiking fever ... Systemic AOSD: high fever ... #rheumatology #diagnosis
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
: • 80% have fever ... 38 degrees • Chills ... Blood cultures • CXR ... ) • CXR upright ... decubitus - air fluid level
Chronic Cough - Differential Diagnosis Algorithm Red Flags: • Fever, night sweats, chills (infection) • Weight loss,
Differential Diagnosis Algorithm ... Red Flags: • Fever ... night sweats, chills ... underlying lung disease ... ) • Abnormal CXR
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
correlates with time of fever ... Daily high spiking fever ... - Fever spikes ... Fever of at least ... #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Adult-onset Still ... • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... Treatment: • Corticosteroids
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... +, Adult-onset Still ... disease, Infection ... #summary #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... common • Imaging: CXR ... Renal Failure Treatment ... #oncology
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Generalized: • Chills ... night sweats, fever ... Complications: Abscess ... Persistent bacteremia/fevers ... diagnosis #management #cardiology
Septic Arthritis - Diagnosis and Management Summary Clinical Exam: hot, swollen, pain with passive AND active ROM
active ROM +/- fever ... , chills, malaise ... necrosis, Lyme disease ... arthritis diagnosis Treatment ... cervical, anal Cxs
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