14 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... triad: Fever, Arthralgia ... #AdultOnset #Stills ... #management #treatment ... #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... : High spiking fever ... Systemic AOSD: high fever ... #rheumatology #diagnosis
Chronic Cough - Differential Diagnosis Algorithm
Red Flags:
 • Fever, night sweats, chills (infection)
 • Weight loss,
Differential Diagnosis Algorithm ... Red Flags: • Fever ... night sweats, chills ... underlying lung disease ... ) • Abnormal CXR
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
correlates with time of fever ... Daily high spiking fever ... - Fever spikes ... Fever of at least ... #diagnosis #rheumatology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
: • 80% have fever ... 38 degrees • Chills ... Blood cultures • CXR ... ) • CXR upright ... decubitus - air fluid level
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Adult-onset Still ... • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... ALT ↑ bilirubin level
In order to better classify heart failure, the American College of Cardiology Foundation and the American
symptoms, can still ... With treatment, ... structural heart disease ... in patients who never ... Classes #NYHA #ACCAHA
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... +, Adult-onset Still ... disease, Infection ... #summary #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... common • Imaging: CXR ... Renal Failure Treatment ... #oncology
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
active ROM +/- fever ... , chills, malaise ... necrosis, Lyme disease ... arthritis diagnosis Treatment ... cervical, anal Cxs