26 results
diagnosis management differential workup comparison hemophagocytic leukemia lymphohistiocytosis syndrome aplastic chronic hodgkins lymphocytic lymphoma testing abscess activation algorithm apml arthritis
Hemophagocytic Lymphohistiocytosis (HLH) Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Clinical Features: Fever ... : ↑↑ ferritin, Anemia ... d-dimer, ↓ NK cell ... 8 criteria: • Fever ... Lymphohistiocytosis #diagnosis #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... Diagnosis #Management #Hematology ... #Rheumatology
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
Disease Acute ... crisis: • Fever ... Supportive with treatment ... hepatomegaly and anemia ... cholestasis: • Fever
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Headaches, bone pain, fever ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... • Autoimmune diseases ... Unknown cause Treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... following: • Fever ... Low or absent NK cell ... • Bicytopenia Treatment ... #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Treatment: • Consider ... stem cell transplant ... if neutropenic fever ... diagnosis #management #treatment ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- Pel-Ebstein fever ... the spleen or liver ... Lymphomas • Other hematologic ... NonHodgkins #comparison #oncology ... #differential #hematology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
- Cr >2 mg/dL or ... 40 ml/min A - Anemia ... diseases, CML, ... MGUS #diagnosis #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... cells can indicate disease ... • Neutropenia, anemia ... microglobulin Treatment ... #hematology
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