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diagnosis management differential hematology infectiousdiseases dermatology disease acute algorithm hemophagocytic hlh lymphohistiocytosis vasculitis cardiology classification emergencies hemeonc hiv leukemia lung
Causes of Acute Onset Fever - Differential Diagnosis Algorithm Viral: • Rhinovirus • Influenza Virus • Parainfluenza
Onset Fever - Differential ... • Thoracic • Abdominal ... Neuroleptic malignant syndrome ... disease • Drug fever ... #Fever #Acute
Summary of Infections in which Steroids play a role in treatment • TB meningitis • TB
play a role in treatment ... pericarditis (select cases ... Severe typhoid fever ... • Ramsay Hunt syndrome ... #management #treatment
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Causes of Pericardial ... Differential Diagnosis Infectious ... , Candida Non-Infectious ... : • Rheumatologic ... Mediterranean Fever
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Causes of Antibiotic ... NMS, serotonin syndrome ... Immunocompromise Treatment ... • Secondary to Treatment ... SJS, DIHS, drug fever
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... risk-stratification • Risks: infection ... only curative treatment ... #hematology #oncology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... ALT ↑ bilirubin level ... #Rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
SLE) - Viral infections ... Kasabach-Merritt syndrome ... APLS • Acute Infectious ... mountain spotted fever ... #rheumatology #
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Neutropenic fever ... : - Fever + ANC ... CT abdomen if abdominal ... or HSCT - CRS: fever ... therapy - Symptoms: fever
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... Treatment: • ... diagnosis #management #treatment ... #summary #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... and petechiae Causes ... index < 2 • EPO Level ... aplastic anemia Treatment ... Aplastic #Anemia #oncology
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