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diagnosis management differential rheumatology algorithm liver syndrome causes acute dermatology hemophagocytic hlh lymphohistiocytosis workup anemia chronic criteria gastroenterology hemeonc injury
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
crisis: • Fever ... Supportive with treatment ... cholestasis: • Fever ... Hepatobiliary #hepatology ... #hepatitis #differential
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
in those with CLD ... months without treatment ... disease, liver ... (DILI) Viral Hepatitis ... Failure #Cirrhosis #Hepatology
Diagnostic criteria for Neutropenic Enterocolitis (NEC) Major Criteria: • Neutropenia (ANC <500 x 10^9 cells/L) • Bowel
30mm length) • Fever ... Criteria: • Abdominal ... distention • Abdominal ... Diagnosis #criteria #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Headaches, bone pain, fever ... , weight loss, abdominal ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- Pel-Ebstein fever ... the spleen or liver ... Lymphomas • Other hematologic ... NonHodgkins #comparison #oncology ... #differential #hematology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Hemochromatosis, Wilson's Disease ... Syndrome, Celiac Disease ... , Infiltrative Disease ... , Sickle Cell, VOD ... Acute #algorithm #hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
breast CA, small cell ... Trauma: Shock liver ... Metabolic: Wilson Disease ... • Autoimmune hepatitis ... Diagnosis #causes #hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Veno-occlusive disease ... Liver disease ... - Alcoholic hepatitis ... Mediterranean fever ... #differential #hepatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... cells can indicate disease ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Clinical triad: Fever ... hepatomegaly, hepatitis ... diagnosis #management #treatment ... #rheumatology
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