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diagnosis differential management disease abnormal aflp ascites causes dili druginduced enzymes fungal hematology hemophagocytic hepatitis hepatobiliary hepatorenal hlh hrs infections
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... liver failure rapidly ... Transfer to a liver ... #Liver #Pregnancy
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
hepatic crisis: • Fever ... Supportive with treatment ... cholestasis: • Fever ... liver failure ... Liver transplant
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Liver disease ... fibrosis - Acute ... fatty liver of ... Mediterranean fever ... #differential #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Alcohol-related liver ... dechallenge • Acute ... #DrugInduced #Liver ... #hepatology
NAFLD Diagnosis Algorithm Two-step diagnostic strategy for NAFLD 1st step: - Clinical biomarkers, scoring systems- FIB4,
inspection of liver ... 2nd step: - Ultrasound-based ... #NonAlcoholic #Fatty ... #Liver #Disease ... #hepatology #NASH
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... derangement of liver ... non-alcoholic fatty ... mellitus; USS, ultrasound ... #Hepatology #Liver
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
presents as an acute ... following: • Fever ... lymph node, or liver ... • Bicytopenia Treatment ... #hematology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
respiratory symptoms • Fever ... Pulmonary 3) Abdominal ... infection • Cough, fever ... normal glucose level ... • Isolated fever
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
Occurs in advanced liver ... liver failure ... • Definitive: Liver ... Treat underlying liver ... • Urgent liver
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