70 results
Hepatitis B Virus Serology and Interpretation
HBsAg - Anti-HBs - Anti-HBc - HBeAg - Anti-HBe
 - Acute
DNA level) or HBeAg-negative ... replication (high HBV ... DNA level) - ... #HBV #Serology ... diagnosis #laboratory #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
HAV immunity; Liver ... elastographv, liver ... Tx goal: Reduce liver ... • Liver is the ... Management #Treatment #Hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
, HCV, HEV, EBV, ... Trauma: Shock liver ... • Autoimmune hepatitis ... Transaminases #hepatitis ... Diagnosis #causes #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... (Drug-induced liver ... Hepatopathy (shock liver ... LouLectures #Liver ... Differential #Diagnosis #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... , HBV, HCV, HEV, ... liver disease, ... cholangitis Consider liver ... #DrugInduced #Liver
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... normal - Infection (EBV ... #Patterns #Liver ... #Injury #hepatology ... #LFTs #transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... Injury → liver ... Hepatocellular Liver ... Differential #Diagnosis #hepatology ... Transaminitis #LFTs
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... infection with severe liver ... mg/dL) or acute liver ... failure #HepatitisB ... Indications #management #hepatology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... Hepatocellular Liver ... or Cholestatic Liver ... #differential #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute Liver ... Hepatocellular - Liver ... Artery: Shock Liver ... Sophia_Hayes_MD #Liver ... Acute #algorithm #hepatology