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liver diagnosis differential management tests transaminitis algorithm chemistry druginduced function gastroenterology injury interpretation laboratory abnormal aflp alkphos astalt bilirubin calling
Drugs and Classes Associated with DILI and Type of Liver Injury #Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... and Type of Liver ... #LiverInjury #Hepatology ... #Pharmacology # ... Causes #DILI
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 Drug-Induced Liver Injury - Pathophysiology Indirect Idiosyncratic Direct BWH Medicine Chiefs @BrighamChiefs #DILI #DrugInduced #Liver #Injury #Pathophysiology #hepatology
Drug-Induced Liver ... Injury - Pathophysiology ... BrighamChiefs #DILI ... #Injury #Pathophysiology ... #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced Liver ... Chronic - ongoing ↑ LFTs ... or symptoms of liver ... Drug #induced #Liver ... gastroenterology #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Tests (LFTs) - ... (>1000): • DILI ... Function #Tests #LFTs ... Differential #Diagnosis #hepatology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... abnormality vs bone Bili ... #FunctionTest #LFTs ... Transaminitis #diagnosis #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... (LFTs) - Normal ... bilirubin (Conjugated/DBili ... Function #Tests #LFTs ... Interpretation #diagnosis #hepatology
The Liver Consult Primer - Guide to calling a consult HPI: - Start with reason for consult
The Liver Consult ... Focus on prior Liver ... - Vitals - LFTs ... GTT, indirect bili ... Calling #Referral #Hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Unconjugated Bili ... > 90% of Total Bili ... #differential #Hepatology ... transaminitis #LFTs
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... 10x ULN), ↑Tbili/Dbili ... Antithrombin Ill • Ultrasound ... #Pregnancy #hepatology ... diagnosis #management #pathophysiology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Liver Chemistry ... In liver, 80% of ... AlkPhos #Bilirubin #Hepatology ... #Pathophysiology ... #Diagnosis #LFTs
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