16 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... months without treatment ... disease, liver ... Injury (DILI) ... Failure #Cirrhosis #Hepatology
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
for Albumin for Management ... • Acute kidney injury ... • Hepatorenal syndrome ... #Cirrhosis #treatment ... #hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
infection with severe liver ... injury (INR > 2 ... mg/dL) or acute liver ... #Indications #management ... #hepatology
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Insufficiency, Liver ... Medications, Spinal Cord Injury ... Abdominal compartment syndrome ... Dehydration Shock Treatment ... #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
thrombocytopenia • Liver ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... - 80% have fever ... : • Pathophysiology ... TLS #diagnosis #management ... #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... hepatocellular pattern of liver ... injury, though ... regarding need for treatment ... #Hepatology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... the setting of liver ... • Underlying liver ... hypertension • Liver ... #treatment #hepatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... lymph node, or liver ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Acute Kidney Injury (AKI) - Management Principles
Prerenal - Correct hemodynamic derangements:
 • If low preload →
Acute Kidney Injury ... (AKI) - Management ... • Hepatorenal syndrome ... Treat underlying liver ... #treatment #management