13 results
Neutropenic Fever Management Algorithm

Temperature > 38°C and ANC < 500/µL

#Neutropenic #Fever #neutropenia #oncology #Management #Algorithm
Neutropenic Fever ... Management Algorithm ... Temperature > 38°C and ANC ... #Fever #neutropenia ... #oncology #Management
Diagnostic criteria for Neutropenic Enterocolitis (NEC)
Major Criteria:
 • Neutropenia (ANC <500 x 10^9 cells/L)
 • Bowel
Criteria: • Neutropenia ... (ANC <500 x 10^ ... 30mm length) • Fever ... Diagnosis #criteria #hematology ... #oncology
Typhlitis - Neutropenic Enterocolitis

Pathophysiology:
 • Chemo → friable intestinal mucosa → bacterial translocation +/- perforation
Presentation:
 •
Typhlitis - Neutropenic ... not abate until ANC ... #Typhlitis #Neutropenic ... Enterocolitis #diagnosis #management ... #oncology #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... ALT ↑ bilirubin level ... Fibrin degradation products ... #Diagnosis #Management ... #Hematology #Rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Difficulty breathing • Neutropenia ... index < 2 • EPO Level ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... Emergencies Neutropenic ... + ANC < 500 → start ... afebrile 24-48 h and ANC ... ICANS: altered level
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Special Blood Product ... RBCs (stored at 4C ... Transfusions #diagnosis #management ... #hematology #reactions
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Subacute-Acute: • Common: fever ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... Diagnosis and Management ... Arterial blood gas (ABC ... hepatopulmonary #syndrome ... #treatment #hepatology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood products contain ... of transfused products ... RBCs (stored at 4C ... Transfusion #diagnosis #management ... #hematology #reactions