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diagnosis hematology blood treatment hemophagocytic hlh lymphohistiocytosis reactions transfusion activation algorithm anemia anticoagulation aplastic apml bloodbank calcium cancer classification common
Diagnostic criteria for Neutropenic Enterocolitis (NEC) Major Criteria: • Neutropenia (ANC <500 x 10^9 cells/L) • Bowel
• Neutropenia (ANC ... 30mm length) • Fever ... Diagnosis #criteria #hematology ... #oncology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... ALT ↑ bilirubin level ... Fibrin degradation products ... #Diagnosis #Management ... #Hematology #Rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Diagnosis and Management ... Myelodysplastic #Syndrome ... #treatment #hematology ... #oncology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
to the relevant product ... Anticoagulation #Management ... #Hematology #Oncology
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 Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... index < 2 • EPO Level ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Consensus Indications for Irradiated RBC Transfusions: Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
disorders (DiGeorge Syndrome ... receiving HLA-selected products ... #Indications #Hematology ... #BloodBank #Management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Subacute-Acute: • Common: fever ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Special Blood Product ... RBCs (stored at 4C ... Transfusions #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood products contain ... of transfused products ... RBCs (stored at 4C ... Transfusion #diagnosis #management ... #hematology #reactions
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... - 80% have fever ... TLS #diagnosis #management ... #hematology
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