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diagnosis management liver differential algorithm lfts nephrology transaminitis acute causes chronic dili failure hbv hematology hepatitis hepatitisb hepatopulmonary indications oncology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... months without treatment ... Injury (DILI) ... #Failure #Cirrhosis ... #Hepatology #gastroenterology
Table of Causes of Acute Liver Injury #Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Table of Causes ... of Acute Liver Injury ... #Diagnosis #Hepatology ... Injury #Causes # ... Differential #Incidence #Table
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Injury (DILI) ... dose dependent injury ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... • NAFLD • Cirrhosis ... (Drug-induced liver ... injury) • Ischemic ... Differential #Diagnosis #hepatology
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
Management of Cirrhosis ... • Acute kidney injury ... Indications #Management #Cirrhosis ... #treatment #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... CMV), Alcoholic cirrhosis ... #Patterns #Liver ... #Injury #hepatology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Family history of cirrhosis ... or fibrosis • Cirrhosis ... injury (INR > 2 ... mg/dL) or acute liver ... Indications #management #hepatology
The Liver Consult Primer - Guide to calling a consult HPI: - Start with reason for consult
The Liver Consult ... Focus on prior Liver ... Gl History - Cirrhosis ... Calling #Referral #Hepatology ... #Gastroenterology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
injury < 26 weeks ... Hepatocellular Level ... hepatocellular injury ... hepatitis: < 1 • Cirrhosis ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Injury: • Hepatic ... Injury: • Infectious ... hepatitis: < 1 • Cirrhosis ... diagnosis #algorithm #hepatology
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