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Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced Liver ... or symptoms of liver ... Drug #induced #Liver ... Idiosyncratic #differential
Upper GI Bleed - Management Algorithm

Upper GI bleed Suspected: Melena, hematemesis, coffee-ground emesis, BRBPR
Initial Stabilization
Concern for
Upper GI Bleed - Management ... Stabilization Concern for Liver ... GAVE (idiopathic, liver ... UGIB #GIBleed #Differential ... gastrointestinal #gastroenterology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... of underlying liver ... disease, liver ... support, or liver ... Cirrhosis #Hepatology #gastroenterology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... Hepatocellular Liver ... or Cholestatic Liver ... Transaminitis #diagnosis #differential
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
The Liver Consult ... Focus on prior Liver ... disease work up - Liver ... GregoryTBrennan #Liver ... Referral #Hepatology #Gastroenterology
Miliary Tuberculosis 
Hematogenous dissemination of Mycobacterium tuberculosis 
Clinical: 
 • Failure to thrive 
 • Fever
to thrive • Fever ... and joints • Liver ... TB #Pulmonary #InfectiousDiseases
Rodent-associated Bacterial infections: Leptospirosis, Rat-bite fever, Tularemia, Plague 

#rodent
#infections
#leptospirosis
#tularemia
#ratbitefever
#plague
#rats
#infectiousdisease
#fever
#differential
#diagnosis
#management
#treatment
#table
Leptospirosis, Rat-bite fever ... plague #rats #infectiousdisease ... #fever #differential ... #diagnosis #management
The Gastroenterology Consult Primer
Guide to Calling a GI Consult
HPI:
 - Start with reason for consult
The Gastroenterology ... consult - I-liner ... Focus on prior GI/Liver ... GregoryTBrennan #Liver ... Calling #Referral #Gastroenterology
Ever had a #traveler come in to your clinic with #fever and you were not sure
Ever had a #traveler ... to narrow your differential ... to narrow your differentials ... #differentials # ... diagnosis #medicine #infectiousdisease
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses
Medical History:
 • Skin exposure to
Regions - Frequent Differential ... amebic abscess of liver ... or elevation of liver ... Typhoid, amebic liver ... fluke, amebic liver