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diagnosis differential hematology management comparison classification dermatology hemeonc hemophagocytic hlh hodgkins leukemia lymphohistiocytosis lymphoma sweet treatment vasculitis activation acute aids
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... SLE], AOSD) • Infection ... ALT ↑ bilirubin level
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
ARDS to explain symptoms ... • Fever and hypotension ... pulmonary edema) • Fever ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
NINDS Diagnostic Criteria for Guillain Barre Syndrome Features Required for Guillain-Barré Syndrome: • Progressive muscle weakness
NINDS Diagnostic Criteria ... , Mild sensory symptoms ... dysfunction, Absence of fever ... Sharp sensory level ... Recent diphtheritic infection
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Neutropenic fever ... : - Fever + ANC ... if SSTI or port infection ... or HSCT - CRS: fever ... : fever, weight
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... /fevers • Thrombocytopenia ... index < 2 • EPO Level ... • Improve the symptoms ... Aplastic #Anemia #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
characterized by fever ... Disorder: - Fever ... : - Fever - ... arthralgia) - Fever ... #dermatology #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
e.g., HIV), EBV infection ... - Pel-Ebstein fever ... Etiology: - Infections ... NonHodgkins #comparison #oncology ... #differential #hematology
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... Pneumonia: • 3 syndromes ... of a "flu-like syndrome ... Constitutional symptoms ... differential #diagnosis #infectiousdiseases
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Headaches, bone pain, fever ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Lymphadenopathy • HSM • Fevers ... #Oncology #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... HLH signs and symptoms ... can mimic common infections ... following: • Fever ... Treatment: • Infection
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