7 results
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Immune Checkpoint ... Complications and ... Treatment #Immune ... #SideEffects #Table ... #Diagnosis #Pharmacology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
nephrotic syndrome ... specific bleeding disorders ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Immune Reconstitution ... Inflammatory Syndrome ... decrease in HIV-1 RNA level ... Drug reaction/ART toxicity ... #Inflammatory #Syndrome
Lithium Therapy for Bipolar Disorder 
Toxicity Levels: 
 - Mild (1-1.5 mEq/L) 
 - Moderate (1.6-2.5
Therapy for Bipolar Disorder ... maintenance agent for treatment ... a target serum level ... order a lithium level ... #Pharmacology #Psychiatry
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Antimicrobial treatment ... required until immune ... • Symptoms: Fever ... Suspect in movement disorders ... opportunistic #InfectiousDiseases
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... activation of the immune ... treatment of the ... Treatment Approach ... malignancy, autoimmune disorder
Alcohol Use Disorder - Maintenance Treatment
Naltrexone (first line) - First line for most people without contraindications
Alcohol Use Disorder ... uptitrate) #AUD ... #Alcohol #Use #Disorder ... #management #pharmacology ... #table #addiction