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diagnosis management dermatology rheumatology acute adjuvant amiodarone antidote clozapine colchicine corticosteroids criteria dermatosis febrile indications induced infections leucovorin lung methotrexate
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... neutrophilic dermatosis (Sweets ... , breast CA - Hematologic ... Treatment: - Systemic ... #dermatology #oncology
Adjuvant therapies in critical care: steroids to treat infectious diseases - Severe Community Acquired Pneumonia
Pneumonia - Typhoid fever ... respiratory distress syndrome ... Corticosteroids #Adjuvant #InfectiousDiseases ... #Infections #Pharmacology ... #Management #Treatment
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
Diagnostic Criteria for Sweet ... Syndrome (Acute ... Fever, temperature ... Excellent response to treatment ... #Syndrome #Acute
Clozapine Toxicology Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... patients who have treatment-resistant ... metabolized in the liver ... #Toxicity #Diagnosis ... #Pharmacology
Phases of Colchicine Toxicity - Early Phase (0-24h) - Multi-organ failure Phase (1-7 days)
Respiratory Distress Syndrome ... edema, myopathy Hematologic ... Renal failure, Liver ... #Toxicology #Phases ... #Pharmacology #
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
starting amiodarone treatment ... respiratory distress syndrome ... Fever 4. ... macrophages Treatment ... diagnosis #management #Toxicology
Methotrexate Toxicology Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
Methotrexate Toxicology ... (folinic acid) treatment ... evidence of marrow toxicity ... #Toxicity #Management ... #Pharmacology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... vasculitis: 10%-16% Liver ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... lubricants • Pharmacologic
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Nonspecific symptoms: Fever ... Polyarteritis Nodosa, GCA, Sweet ... syndrome, MDS & ... affected tissue Treatment ... Polychondritis #rheumatology
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