51 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced Liver ... ongoing ↑ LFTs or symptoms ... of liver disease ... Drug #induced #Liver
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Pathogenesis and clinical ... #Syndromes #diagnosis ... #pathophysiology ... #signs #symptoms ... #msk #orthopedics
Complications of Measles: Pathogenesis and Clinical Findings
 • ADEM -> Fever, headache, neck stiffness, BBD, mental
Pathogenesis and Clinical ... N/V, elevated liver ... Complications #diagnosis ... #signs #symptoms ... #pathophysiology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... malaise) → Acute liver ... Transfer to a liver ... #management #pathophysiology
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
Clinical manifestations ... of acute liver ... abnormalities Liver ... manifestations #acute #liver ... #Diagnosis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... Failure (ACLF) Clinical ... disease, liver ... Injury (DILI) ... #diagnosis
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Workup • CNS symptoms ... Returning Traveler’ algorithm ... duplex or CTA • Liver ... Liver biopsy • ... node biopsy • Clinical
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... the diagnosis and ... suspected HH based on symptoms ... , elevated liver ... #diagnosis #management
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... cycle found in the liver ... and acute kidney injury ... also includes symptoms ... #Management
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Pathogenesis and Clinical ... cells -> Tissue injury ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications