44 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... : fever, myalgias ... • Imaging: CXR ... #management #hematology ... #oncology
Chilaiditi Sign on Chest X-Ray
Anterior interposition of the colon between the hemidiaphragm and the liver.
Chilaiditi sign
interposition of the colon ... thus important to diagnose ... #Sign #Chest #XRay ... #CXR #clinical ... #radiology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... and Management ... Myelodysplastic #Syndrome ... #Management #treatment ... #hematology #oncology
Pneumoperitoneum vs Pseudo-Pneumoperitoneum aka Chilaiditi Sign
It mimics pneumoperitoneum and it is thus important to diagnose it
thus important to diagnose ... the large gut (commonly ... ) between the liver ... Sign #clinical #radiology ... #cxr #xray #chest
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... syndromes Clinical ... hypersensitivity syndromes ... #Diagnosis #Management ... #Hematology #Rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Non-specific; common ... Dermatomyositis Anti-LKM (liver ... La) - Sjogren's syndrome ... Associations #diseases #diagnosis ... #table #rheumatology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Disease (KD) - Diagnosis ... and Management ... KD) is the most common ... Criteria - Fever ... KD #vasculitis #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... - 80% have fever ... acid, Elevated Cr ... #TLS #diagnosis ... #management #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Low serum IgG level ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... symptoms can mimic common ... following: • Fever ... #management #treatment ... #hematology